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先天性门体分流合并早期胃癌患者行脾肾分流切除术后肝脏体积增大。日本病例回顾。

Resection of spleno-renal shunt resulting in enhanced liver volume in a patient with congenital portosystemic shunt concomitant with early gastric cancer. Review of Japanese cases.

作者信息

Sato Y, Mitsuma C, Iwaya A, Kurosaki I, Shirai Y, Hatakeyama K

机构信息

First Department of Surgery, Niigata University, School of Medicine, Niigata, Japan.

出版信息

Dig Surg. 2001;18(1):74-8. doi: 10.1159/000050102.

Abstract

A 73-year-old man recurring hepatic encephalopathy due to a congenital splenorenal shunt concomitant with early gastric cancer was successfully treated by surgical intervention. The portal pressures before and after the shunt resection were 13.5 and 18 cm H2O, respectively. The liver was slightly atrophic and the histological specimen showed slight fibrosis and mild infiltration of lymphocytes in the portal area. After the operation, the encephalopathy was improved and the several factors of liver function also recovered. Interestingly, the liver volume estimated by abdominal CT clearly increased 1 month after the shunt resection. The encephalopathy in congenital portosystemic shunt might result from chronic liver ischemia and atrophy. Moreover, the shunt resection may enlarge the functional liver volume by increasing the portal blood flow.

摘要

一名73岁男性因先天性脾肾分流伴早期胃癌反复出现肝性脑病,经手术干预成功治愈。分流切除术前和术后的门静脉压力分别为13.5 cmH₂O和18 cmH₂O。肝脏轻度萎缩,组织学标本显示门管区有轻度纤维化和淋巴细胞轻度浸润。术后,脑病得到改善,肝功能的几个指标也恢复正常。有趣的是,分流切除术后1个月,腹部CT估计的肝脏体积明显增加。先天性门体分流性脑病可能是由慢性肝脏缺血和萎缩引起的。此外,分流切除术可能通过增加门静脉血流来扩大功能性肝体积。

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