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冲洗、清创和抗生素治疗能治愈全髋关节置换术的感染吗?

Could irrigation, debridement and antibiotic therapy cure an infection of a total hip arthroplasty?

作者信息

Krasin E, Goldwirth M, Hemo Y, Gold A, Herling G, Otremski I

机构信息

Department of Orthopaedics 'A', Tel Aviv Sourasky Medical Centre and the Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.

出版信息

J Hosp Infect. 2001 Mar;47(3):235-8. doi: 10.1053/jhin.2000.0809.

DOI:10.1053/jhin.2000.0809
PMID:11247685
Abstract

Seven patients suffering from an acute (less than two weeks) infection of a total hip arthroplasty were treated by irrigation and debridement, with appropriate antibiotic therapy and retention of the prosthesis. They were followed for an average of 30 months. Infection did not recur in five (71%) patients, but the other two required further surgery. We conclude that a cure can be obtained by this method, although the results are inferior to re-implantation. A minimal procedure spares a patient the morbidity and cost of a more extensive operation. Higher success rates might have been achieved by selecting patients infected with organisms of low virulence, but there are insufficient data to predict whether this treatment would decrease the success of subsequent re-implantation.

摘要

七名全髋关节置换术后发生急性(少于两周)感染的患者接受了冲洗清创术,并给予适当的抗生素治疗,同时保留假体。对他们进行了平均30个月的随访。五名(71%)患者感染未复发,但另外两名患者需要进一步手术。我们得出结论,尽管该方法的结果不如再次植入,但通过这种方法可以实现治愈。一个微创的手术可以使患者避免更广泛手术带来的发病率和费用。通过选择感染低毒力微生物的患者可能会获得更高的成功率,但目前尚无足够的数据来预测这种治疗是否会降低后续再次植入的成功率。

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引用本文的文献

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SICOT J. 2019;5:5. doi: 10.1051/sicotj/2019004. Epub 2019 Feb 28.
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Acute compartment syndrome of the leg due to infection following an insect bite: A case report.昆虫叮咬后感染所致小腿急性骨筋膜室综合征:一例报告
Medicine (Baltimore). 2018 Jul;97(30):e11613. doi: 10.1097/MD.0000000000011613.
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Biofilm and the Role of Antibiotics in the Treatment of Periprosthetic Hip and Knee Joint Infections.
生物膜以及抗生素在人工髋关节和膝关节周围感染治疗中的作用
Open Orthop J. 2016 Nov 30;10:636-645. doi: 10.2174/1874325001610010636. eCollection 2016.
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Can periprosthetic hip joint infections be successfully managed by debridement and prosthesis retention?髋关节假体周围感染能否通过清创和保留假体成功治疗?
World J Orthop. 2014 Jul 18;5(3):218-24. doi: 10.5312/wjo.v5.i3.218.
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Aggressive early débridement for treatment of acutely infected cemented total hip arthroplasty.积极的早期清创术治疗急性感染的骨水泥固定全髋关节置换术。
Clin Orthop Relat Res. 2012 Nov;470(11):3164-70. doi: 10.1007/s11999-012-2500-7.
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Failure of irrigation and débridement for early postoperative periprosthetic infection.早期术后假体周围感染的灌洗和清创失败。
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