病毒性迷路炎——一项实验研究。

Viral labyrinthitis -- an experimental study.

作者信息

Karmody C S

出版信息

Ann Otol Rhinol Laryngol. 1975 Mar-Apr;84(2 PART 1):179-81. doi: 10.1177/000348947508400206.

Abstract

Summary--An attempt was made to produce viral labyrinthitis in the rhesus monkey. Rhesus monkeys are susceptible to the mumps virus. Nine animals were used. After removal of the stapes, the left oval windows were plugged with Gelfoam soaked in a culture of live mumps virus; right oval windows were plugged with Gelfoam soaked in killed cultures. Animals were sacrificed at different time intervals, postinfection. In eight of the nine animals there was seroconversion from negative to positive; however, none of the animals developed the histologic changes of viral labyrinthitis.

摘要

摘要——尝试在恒河猴身上诱发病毒性迷路炎。恒河猴对腮腺炎病毒易感。使用了9只动物。切除镫骨后，用浸泡在活腮腺炎病毒培养物中的明胶海绵堵塞左侧椭圆窗；右侧椭圆窗用浸泡在灭活培养物中的明胶海绵堵塞。在感染后的不同时间间隔处死动物。9只动物中有8只出现了血清学从阴性转为阳性的情况；然而，没有一只动物出现病毒性迷路炎的组织学变化。