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类风湿关节炎中滑膜组织学与关节损伤之间缺乏相关性。

Lack of correlation of synovial histology with joint damage in rheumatoid arthritis.

作者信息

Henderson D R, Jayson M I, Tribe C R

出版信息

Ann Rheum Dis. 1975 Feb;34(1):7-11. doi: 10.1136/ard.34.1.7.

DOI:10.1136/ard.34.1.7
PMID:1124957
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1006339/
Abstract

Twenty-two patients with rheumatoid arthritis (RA) involving the knee were studied. The systemic features of the disease were graded and the extent of knee involvement was quantified in terms of the clinical, radiological, and arthroscopic appearances. Adequate synovial biopsies were obtained from 21 patients. In these patients no correlation could be found between the severity of any of the features on histological examination nor between any of these features and the extent of local joint damage, inflammation, or the severity of the systemic disease.

摘要

对22例累及膝关节的类风湿性关节炎(RA)患者进行了研究。对该疾病的全身特征进行分级,并根据临床、放射学和关节镜检查结果对膝关节受累程度进行量化。从21例患者身上获取了足够的滑膜活检样本。在这些患者中,组织学检查的任何特征的严重程度之间,以及这些特征中的任何一个与局部关节损伤、炎症或全身疾病的严重程度之间均未发现相关性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8fae/1006339/e98b0d83fd74/annrheumd00026-0017-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8fae/1006339/d25e712e48c2/annrheumd00026-0016-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8fae/1006339/e98b0d83fd74/annrheumd00026-0017-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8fae/1006339/d25e712e48c2/annrheumd00026-0016-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8fae/1006339/e98b0d83fd74/annrheumd00026-0017-a.jpg

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引用本文的文献

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Synovial biopsy in arthritis research: five years of concerted European collaboration.关节炎研究中的滑膜活检:欧洲五年的协同合作。
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Immunohistochemical analysis of proliferating and antigen-presenting cells in rheumatoid synovial tissue.类风湿性滑膜组织中增殖细胞和抗原呈递细胞的免疫组织化学分析

本文引用的文献

1
BIOCHEMICAL EVENTS IN JOINT DISEASE.
J Chronic Dis. 1963 Aug;16:835-52. doi: 10.1016/0021-9681(63)90134-6.
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DIAGNOSTIC criteria for rheumatoid arthritis: 1958 revision by a committee of the American Rheumatism Association.类风湿关节炎的诊断标准:美国风湿病协会委员会1958年修订版。
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Do lymphocytes protect the rheumatoid joint?淋巴细胞能保护类风湿性关节吗?
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Immunohistological analysis of the synovial membrane: search for predictors of the clinical course in rheumatoid arthritis.滑膜的免疫组织学分析:寻找类风湿关节炎临床病程的预测指标
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Correlative histologic and arthroscopic evaluation in rheumatoid knee joints.类风湿性膝关节的组织学与关节镜相关性评估
Surg Endosc. 1992 Nov-Dec;6(6):277-82. doi: 10.1007/BF02498859.
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Indications for arthroscopy in mon- and polyarticular arthritis.单关节和多关节关节炎的关节镜检查适应症。
Ann Rheum Dis. 1979 Aug;38(4):337-40. doi: 10.1136/ard.38.4.337.
4
Correlation of histochemical, histologic and biochemical evaluations of human synovium with clinical activity.人类滑膜组织化学、组织学及生化评估与临床活动度的相关性
Arthritis Rheum. 1973 May-Jun;16(3):376-82. doi: 10.1002/art.1780160313.
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The anaemia of rheumatoid arthritis: the significance of iron deposits in the synovial membrane.类风湿关节炎的贫血:滑膜中铁沉积的意义。
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