爵床属木脂素VI——前列腺素D，一种来自平卧爵床（Justicia diffusa var. prostrata C.B. Clarke）的新型芳基萘类木脂素。

Justicia lignans VI--prostalidin D, a new arylnaphthalide lignan from Justicia diffusa var. prostrata C.B. Clarke.

作者信息

Rajasekhar D, Subbaraju G V, Pillai K R

机构信息

Department of Chemistry, Sri Venkateswara University, Tirupati, India.

出版信息

J Asian Nat Prod Res. 2000;2(4):289-300. doi: 10.1080/10286020008041368.

DOI:10.1080/10286020008041368

PMID:11249611

Abstract

A new arylnaphthalide lignan, prostalidin D (6) was isolated as a minor metabolite from Justicia diffusa var. prostrata. 6 contains a rare catechol unit and its structure was confirmed by total synthesis. In addition, seven known lignans, namely, justicidin E (7), helioxanthin (8), justicidin A (9), medioresinol dimethyl ether (10), medioresinol (11), lariciresinol (12) and 8-methoxyisolariciresinol (13) have also been isolated from the same source and identified by direct comparison with authentic samples.

摘要

从平卧腺毛马蓝中分离得到一种新的芳基萘内酯木脂素——前列腺素D（6），它是一种次要代谢产物。6含有一个罕见的儿茶酚单元，其结构通过全合成得以确证。此外，还从同一来源分离得到了七种已知木脂素，即正义霉素E（7）、半日花素（8）、正义霉素A（9）、中树脂醇二甲醚（10）、中树脂醇（11）、落叶松脂醇（12）和8-甲氧基异落叶松脂醇（13），并通过与标准样品直接比较进行了鉴定。