Chen D F, Zhang S X, Chen K, Zhou B N, Wang P, Cosentino L M, Lee K H
Department of Pharmacognosy, School of Pharmacy, Shanghai Medical University, People's Republic of China.
J Nat Prod. 1996 Nov;59(11):1066-8. doi: 10.1021/np9601667.
Two new lignans, interiotherins A (1) and B (2), along with two known lignans, angeloylgomisin R (3) and schisantherin D (4), were isolated from Kadsura interior. Their structures and stereochemistries were determined from spectral data. Compounds 1 and 4 inhibit HIV replication with EC50 values of 3.1 and 0.5 micrograms/mL, respectively.
从黑老虎中分离得到两个新的木脂素，内南五味子素A（1）和B（2），以及两个已知木脂素，当归酰戈米辛R（3）和南五味子素D（4）。通过光谱数据确定了它们的结构和立体化学。化合物1和4对HIV复制具有抑制作用，其半数有效浓度（EC50）值分别为3.1和0.5微克/毫升。
