Tepass U, Truong K, Godt D, Ikura M, Peifer M
Department of Zoology, University of Toronto, 25 Harbord Street, Toronto, Ontario M5S 3G5, Canada.
Nat Rev Mol Cell Biol. 2000 Nov;1(2):91-100. doi: 10.1038/35040042.
Cadherins not only maintain the structural integrity of cells and tissues but also control a wide array of cellular behaviours. They are instrumental for cell and tissue polarization, and they regulate cell movements such as cell sorting, cell migration and cell rearrangements. Cadherins may also contribute to neurite outgrowth and pathfinding, and to synaptic specificity and modulation in the central nervous system.
钙黏蛋白不仅维持细胞和组织的结构完整性，还控制着一系列广泛的细胞行为。它们对细胞和组织的极化至关重要，并且调节细胞运动，如细胞分选、细胞迁移和细胞重排。钙黏蛋白也可能有助于神经突生长和路径寻找，以及中枢神经系统中的突触特异性和调节。
