Perlman S E, Leach E E, Dominguez L, Ruszkowski A M, Rudy S J
Department of Obstetrics and Gynecology, University of Louisville School of Medicine, Louisville, Kentucky, USA.
J Reprod Med. 2001 Feb;46(2 Suppl):179-85.
After studying the information in this article, the reader should be able to: 1. Describe the purpose of the pregnancy prevention program. 2. Discuss the five most common reasons for unintended pregnancy. 3. List the components of the expanded pregnancy prevention program. Preventing unintended pregnancy is currently an unsolved problem in the United States, especially among teens. However, successful programs to minimize unintended pregnancy do exist and can serve as a model for other efforts. One such program is the Pregnancy Prevention Program, for use when prescribing isotretinoin to women with childbearing potential. Isotretinoin is a known teratogen and is prescribed disproportionately to teens, who are at higher risk of unintended pregnancy. The program has shown impressive effectiveness despite these handicaps, but since exposure to isotretinoin is so harmful to the fetus and some women still become pregnant while taking the drug, the program has been revised to reduce the failure rate further.
在研读本文中的信息后，读者应能够：1. 描述预防怀孕计划的目的。2. 讨论意外怀孕的五个最常见原因。3. 列出扩展的预防怀孕计划的组成部分。目前，预防意外怀孕在美国仍是一个未解决的问题，尤其是在青少年中。然而，确实存在成功将意外怀孕风险降至最低的计划，这些计划可为其他相关工作提供范例。其中一个计划就是预防怀孕计划，用于在给有生育潜力的女性开异维A酸处方时。异维A酸是一种已知的致畸剂，且在青少年中开处方的比例过高，而青少年意外怀孕的风险更高。尽管存在这些不利因素，该计划仍显示出令人瞩目的成效，但由于接触异维A酸对胎儿危害极大，且一些女性在服药期间仍会怀孕，因此该计划已进行修订，以进一步降低失败率。
