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痴呆和非痴呆老年人的直接死因。

Immediate causes of death of demented and non-demented elderly.

作者信息

Kammoun S, Gold G, Bouras C, Giannakopoulos P, McGee W, Herrmann F, Michel J P

机构信息

Department of Geriatrics, Geneva University Hospitals, Switzerland.

出版信息

Acta Neurol Scand Suppl. 2000;176:96-9. doi: 10.1034/j.1600-0404.2000.00314.x.

DOI:10.1034/j.1600-0404.2000.00314.x
PMID:11261812
Abstract

OBJECTIVE

To investigate the immediate causes of death, in autopsied demented and non-demented elderly.

DESIGN

Retrospective clinicopathologic correlations.

SETTING

Acute and intermediate care geriatric hospital.

PARTICIPANTS

342 hospitalized demented and non-demented elderly (mean age 84.94 +/- 6.9 years) who underwent consecutive postmortem examinations: 120 demented patients with either vascular dementia (VaD, n = 34), mixed dementia (MD, n = 65) or Alzheimer's disease (AD, n=21) neuropathologically confirmed and 222 nondemented elderly.

RESULTS

Primary causes of death were similar in both demented and non-demented patients; the commonest were cardiovascular disease and bronchopneumonia. Cardiac causes of death and especially cardiac failure were more frequent in VaD than in AD or MD (respectively P = 0.027 and 0.005). Dementia was an underlying but never a primary cause of death.

CONCLUSIONS

Immediate causes of death are similar in elderly demented and non-demented patients.

摘要

目的

调查经尸检的老年痴呆患者和非痴呆患者的直接死因。

设计

回顾性临床病理相关性研究。

地点

急性和中级护理老年医院。

参与者

342名住院的老年痴呆患者和非痴呆患者(平均年龄84.94±6.9岁),他们接受了连续的尸检:120名痴呆患者,其中血管性痴呆(VaD,n = 34)、混合性痴呆(MD,n = 65)或阿尔茨海默病(AD,n = 21)经神经病理学确诊,以及222名非痴呆老年患者。

结果

痴呆患者和非痴呆患者的主要死因相似;最常见的是心血管疾病和支气管肺炎。VaD患者中心脏病导致的死亡,尤其是心力衰竭,比AD或MD患者更常见(分别为P = 0.027和0.005)。痴呆是潜在死因,但绝非直接死因。

结论

老年痴呆患者和非痴呆患者的直接死因相似。

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