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阿尔茨海默病和血管性痴呆中的医学病症。

Medical disorders in Alzheimer's disease and vascular dementia.

作者信息

Förstl H, Cairns N, Burns A, Luthert P

机构信息

Department of Old Age Psychiatry, MRC Alzheimer Disease Brain Bank, London, UK.

出版信息

Postgrad Med J. 1991 Aug;67(790):742-4. doi: 10.1136/pgmj.67.790.742.

Abstract

The clinical and postmortem findings of 29 patients with Alzheimer's disease were evaluated and compared to the findings of 19 patients with vascular dementia. The patients with Alzheimer's disease had received treatment for an average of 2.0 internal medical disorders, the patients with vascular dementia for 2.1 disorders. The average number of medical diseases found at postmortem was 3.7 in the group with Alzheimer's dementia and 4.1 in vascular dementia. Apart from a marginally increased rate of peripheral occlusive artery disease in vascular dementia, the proportions of the most common disorders of the cardiovascular, genitourinary, gastrointestinal and endocrinological disorders and the most common causes of death did not differ significantly between these groups. Therefore patients with Alzheimer's disease should receive the same internal medical attention as patients with vascular dementia.

摘要

对29例阿尔茨海默病患者的临床和尸检结果进行了评估,并与19例血管性痴呆患者的结果进行了比较。阿尔茨海默病患者平均接受过2.0种内科疾病的治疗,血管性痴呆患者为2.1种疾病。在尸检中发现,阿尔茨海默病痴呆组的平均疾病数为3.7种,血管性痴呆组为4.1种。除血管性痴呆患者外周闭塞性动脉疾病发生率略有增加外,这些组中心血管、泌尿生殖、胃肠道和内分泌系统最常见疾病的比例以及最常见死因并无显著差异。因此,阿尔茨海默病患者应接受与血管性痴呆患者相同的内科关注。

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本文引用的文献

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J Am Geriatr Soc. 1985 Aug;33(8):530-7. doi: 10.1111/j.1532-5415.1985.tb04616.x.
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Are Alzheimer patients healthier?老年痴呆症患者更健康吗?
J Am Geriatr Soc. 1988 Mar;36(3):219-24. doi: 10.1111/j.1532-5415.1988.tb01804.x.
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The risk factors for Alzheimer's disease: a review and a hypothesis.阿尔茨海默病的风险因素:综述与假说
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