Bartlett R H, Gazzaniga A B, Wilson A F, Medley T, Wetmore N
Chest. 1975 Jun;67(6):680-4. doi: 10.1378/chest.67.6.680.
The results of treatment of acute respiratory insufficiency in the adult must be quantitated before indications for innovative treatment (such as extracorporeal oxygenation) can be defined. A method for retrospective and prospective data collection based on a graph of A-a gradient and time was evaluated in 45 patients. From this graph a pulmonary insufficiency index (PII) can be calculated which correlates well with mortality in this series. The mean PII of surviving patients was 0.84 and the highest value was 2.75. The mean PII of patients who died with pulmonary insufficiency was 15.9; the lowest value was 6.0. Using this method with a larger data base, it will be possible to predict mortality based on PII facilitating the study of ongoing management and innovative treatment methods.
在确定创新治疗（如体外氧合）的指征之前，必须对成人急性呼吸功能不全的治疗结果进行量化。我们对45例患者评估了一种基于A-a梯度与时间关系图进行回顾性和前瞻性数据收集的方法。通过该图可计算出肺功能不全指数（PII），在本系列研究中，该指数与死亡率密切相关。存活患者的平均PII为0.84，最高值为2.75。死于肺功能不全患者的平均PII为15.9，最低值为6.0。利用该方法并基于更大的数据库，将有可能根据PII预测死亡率，从而有助于对现行治疗管理和创新治疗方法的研究。
