Mancebo J, Benito S, Martín M, Net A
Servei de Medicina Intensiva, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain.
Intensive Care Med. 1988;14(2):110-4. doi: 10.1007/BF00257461.
The measurement of static pulmonary compliance by means of pressure-volume curves is an useful tool in the management of patients with acute respiratory failure. On admission to our Intensive Care Unit, we calculated the static pulmonary compliance values from the pressure-volume curve in 55 severe acute respiratory failure patients under mechanical ventilation. A predictive model, based on static pulmonary compliance measured on the deflation of the pressure-volume curve and patients' age, was developed using a function derived by stepwise discriminant analysis. Thirty-six of the 40 patients (90%) in the learning sample and 12 of the 15 patients (80%) in the test sample were correctly classified into survivors or non-survivors. The overall classification demonstrated an accuracy of 88% (48 of 55 patients). We conclude that the value of static pulmonary compliance can be an useful prognostic factor in patients with severe acute respiratory failure.
通过压力-容积曲线测量静态肺顺应性是管理急性呼吸衰竭患者的一项有用工具。在患者入住我们的重症监护病房时，我们根据压力-容积曲线计算了55例接受机械通气的严重急性呼吸衰竭患者的静态肺顺应性值。利用逐步判别分析得出的函数，建立了一个基于压力-容积曲线放气时测得的静态肺顺应性和患者年龄的预测模型。学习样本中的40例患者中有36例（90%），测试样本中的15例患者中有12例（80%）被正确分类为存活者或非存活者。总体分类的准确率为88%（55例患者中的48例）。我们得出结论，静态肺顺应性值可能是严重急性呼吸衰竭患者的一个有用的预后因素。
