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[传统地方性病区学校人群中甲状腺肿和碘缺乏症的患病率]

[Prevalence of goitre and iodine deficiency in a school population from a traditionally endemic health area].

作者信息

Madueño Caro A J, Cabezas Saura P B, Díaz Orta J, Benítez Rodríguez E, Ruiz Galdón M, Gómez A

机构信息

Centro de Salud de Olvera, Cádiz.

出版信息

Aten Primaria. 2001 Mar 15;27(4):258-62. doi: 10.1016/S0212-6567(01)78805-1.

Abstract

OBJECTIVES

To determine the current prevalence of simple goitre in the school population of a health district where goitre is traditionally endemic. Calculation of the deficiency or otherwise of iodine through the determination of mean urinary excretion of iodine in the population under study.

DESIGN

Cross-sectional descriptive study.

SETTING

Olvera Health District (Cádiz).

PARTICIPANTS

School students in the health district between 6 and 14 years old out of a total of 1969. Sample size of 92 school students was chosen at random, for a 95% confidence interval.

MEASUREMENTS AND MAIN RESULTS

Dependent variables were the existence of goitre found in a physical examination, urinary excretion of iodine measured in microg/dl in the first urine of the morning, origin of water consumed and habitual consumption of iodised salt in their diet. 87% of the population under study habitually drank water from the normal supply, 4% from wells or springs, and 9% mineral water. 57% of parents did not know whether the salt in their normal diet was iodised or not. 29.3% of school students included in the study had some degree of goitre. The mean excretion of iodine in urine was 13.78 microg/dl (95% CI, 12.30-15.26). Ioduria was below 9.9 microg/dl in 28.2%, within the endemic figures.

CONCLUSIONS

The mean amount of iodine in urinary excretion in the sample means that the risk of developing goitre is low, although the prevalence of goitre continues at endemic figures.

摘要

目的

确定在一个甲状腺肿传统上呈地方性流行的健康区学校人群中单纯性甲状腺肿的当前患病率。通过测定研究人群尿碘平均排泄量来计算碘缺乏与否。

设计

横断面描述性研究。

地点

奥尔韦拉健康区(加的斯)。

参与者

该健康区6至14岁的在校学生,共1969人。随机选择92名在校学生作为样本,置信区间为95%。

测量与主要结果

因变量包括体检中发现的甲状腺肿情况、晨尿中以微克/分升为单位测量的尿碘排泄量、所饮用的水源以及饮食中碘盐的习惯性摄入量。87%的研究人群习惯性饮用正常供应的水,4%饮用井水或泉水,9%饮用矿泉水。57%的家长不知道其日常饮食中的盐是否加碘。纳入研究的在校学生中有29.3%有一定程度的甲状腺肿。尿碘平均排泄量为13.78微克/分升(95%可信区间,12.30 - 15.26)。28.2%的人群尿碘低于9.9微克/分升,处于地方性流行水平。

结论

样本中尿碘的平均含量表明患甲状腺肿的风险较低,尽管甲状腺肿患病率仍维持在地方性流行水平。

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Iodine-deficiency disorders.碘缺乏症
Lancet. 1988 Jun 18;1(8599):1386-7. doi: 10.1016/s0140-6736(88)92193-9.

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