Cawse J N
Combinatorial Chemistry Program, GE Corporate R&D, General Electric Company, P.O. Box 8, Schenectady, New York 12301, USA.
Acc Chem Res. 2001 Mar;34(3):213-21. doi: 10.1021/ar000117s.
As high-throughput experimental techniques have become common in the area of materials research, entirely new types of experimental strategies have appeared. The kinds of problems, the desired outcomes, and the appropriate patterns are significantly different from those associated with conventional experimentation. Classical experimental design (design of experiments, DOE) strategies grew up in a period of slow, laborious, error-prone experimentation; a modern high-throughput laboratory can test more materials in a week than was previously done in a year. The goal of this Account is to identify and critically discuss some of the strategies that are being developed and used in this new, exciting area of research.
随着高通量实验技术在材料研究领域变得普遍，全新类型的实验策略应运而生。这类问题、预期结果以及合适的模式与传统实验所涉及的显著不同。经典实验设计（实验设计，DOE）策略是在实验缓慢、费力且容易出错的时期发展起来的；一个现代高通量实验室一周内能够测试的材料比以往一年测试的还要多。本综述的目的是识别并批判性地讨论在这个新的、令人兴奋的研究领域中正在开发和使用的一些策略。
