Ito K, Hungerbühler R, Wahl D, Grass R
Cartilege Biomechanics Group, AO/ASIF Research Institute, Clavadelerstrasse, CH-7270 Davos-Platz, Switzerland.
J Orthop Trauma. 2001 Mar-Apr;15(3):192-6. doi: 10.1097/00005131-200103000-00008.
Intramedullary nail locking bolts often fail to gain purchase or cut out in osteoporotic bone. The biomechanical stability of a bladelike device that lowers intraosseous stress levels by distributing the load over a greater volume of bone was compared with conventional locking bolts in osteoporotic bone.
Standardized simulated comminuted supracondylar femoral fractures (segmental defect) in fresh-frozen paired osteoporotic (bone mineral density <200 milligrams per cubic centimeter) human cadaveric femurs were stabilized with a retrograde unreamed distal femoral nail and distally interlocked with conventional locking bolts or a bladelike device. The distal portions of the fixator-bone constructs were tested under axial load, and the stiffness and strength were compared (pairwise).
Interlocking with a bladelike device was 41 percent stiffer (p = 0.01) and 20 percent stronger (p = 0.02) than that with conventional locking bolts. All posttesting radiographs showed compaction of the cancellous bone distal to the interlocking devices. Even after nail displacements of twelve millimeters, only a few locking bolts were plastically deformed and no bladelike device showed gross plastic deformation.
This study showed the biomechanical benefits of increasing the bone-implant interface surface for improving the acute stiffness and strength of fracture fixation in osteoporotic cancellous bone. The fixator-bone construct withstood higher forces before failure in these fragile bones.
髓内钉锁定螺栓在骨质疏松性骨中常无法获得足够的把持力或穿出。将一种通过在更大骨体积上分散负荷来降低骨内应力水平的刀片状装置与传统锁定螺栓在骨质疏松性骨中的生物力学稳定性进行比较。
在新鲜冷冻的配对骨质疏松性(骨矿物质密度<200毫克每立方厘米)人体尸体股骨中制造标准化的模拟股骨髁上粉碎性骨折(节段性缺损),用逆行非扩髓股骨远端髓内钉固定,并在远端用传统锁定螺栓或刀片状装置进行锁定。对固定器-骨结构的远端部分进行轴向加载测试,并比较其刚度和强度(成对比较)。
与传统锁定螺栓相比,使用刀片状装置锁定时刚度高41%(p = 0.01),强度高20%(p = 0.02)。所有测试后的X线片均显示锁定装置远端的松质骨有压缩。即使在髓内钉移位12毫米后,只有少数锁定螺栓发生塑性变形,没有刀片状装置出现明显塑性变形。
本研究显示了增加骨-植入物界面面积对提高骨质疏松性松质骨骨折固定的急性刚度和强度的生物力学益处。在这些脆弱的骨骼中,固定器-骨结构在失效前能承受更高的力。