Dutt N, Berney D M
Department of Morbid Anatomy and Histopathology, St Bartholomew's Hospital, West Smithfield, London EC1A 7BE, UK.
J Clin Pathol. 2000 Dec;53(12):938-9. doi: 10.1136/jcp.53.12.938.
A 57 year old woman presented complaining of increasing abdominal swelling of six months duration. A mixed solid cystic left ovarian tumour measuring 24 cm in diameter was excised. Histology showed numerous cysts lined by benign mucinous epithelium blending imperceptibly into borderline clear cell and mucinous areas that in turn merged with an invasive clear cell carcinoma. To the best of our knowledge, this is the first reported case of clear cell carcinoma arising in a mucinous cystadenoma. The implications for the previously postulated pathogenesis of these tumours are discussed.
一名57岁女性因腹部肿胀持续6个月加重前来就诊。切除了一个直径24厘米的左卵巢混合实性囊性肿瘤。组织学检查显示，众多囊肿内衬良性黏液上皮，难以察觉地融合到交界性透明细胞和黏液区域，这些区域又与浸润性透明细胞癌相连。据我们所知，这是首例报道的黏液性囊腺瘤中发生透明细胞癌的病例。文中讨论了这些肿瘤先前假定发病机制的意义。
