Xiao L, Limor J, Bern C, Lal A A
Division of Parasitic Diseases, Centers for Disease Control and Prevention, Mail Stop F12, Atlanta, GA 30333, USA.
Emerg Infect Dis. 2001 Jan-Feb;7(1):141-5. doi: 10.3201/eid0701.010121.
We sequenced a 173-nucleotide fragment of the small double-stranded viruslike RNA of Cryptosporidium parvum isolates from 23 calves and 38 humans. Sequence diversity was detected at 17 sites. Isolates from the same outbreak had identical double-stranded RNA sequences, suggesting that this technique may be useful for tracking Cryptosporidium infection sources.
我们对来自23头小牛和38名人类的微小隐孢子虫分离株的双链病毒样小RNA的173个核苷酸片段进行了测序。在17个位点检测到序列多样性。来自同一疫情爆发的分离株具有相同的双链RNA序列,这表明该技术可能有助于追踪隐孢子虫感染源。