New cyclic depsipeptide antibiotics, clavariopsins A and B, produced by an aquatic hyphomycetes, Clavariopsis aquatica. 1. Taxonomy, fermentation, isolation, and biological properties.
作者信息
Kaida K, Fudou R, Kameyama T, Tubaki K, Suzuki Y, Ojika M, Sakagami Y
机构信息
Pharmaceutical Research Laboratories, Ajinomoto Co, Inc.
出版信息
J Antibiot (Tokyo). 2001 Jan;54(1):17-21. doi: 10.7164/antibiotics.54.17.
PMID:11269710
Abstract
Clavariopsins were isolated from the fermentation broth of Clavariopsis aquatica AJ 117363. Clavariopsins are cyclic depsipeptide antibiotics with the molecular weight of 1,153 and 1,139. Clavariopsins showed in vitro antifungal activity against not only Aspergillus fumigatus but also, although to a lesser extent, A. niger and Candida albicans.
摘要
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