Saary M, Sissons J G, Davies W A, Hoffbrand A V
J Clin Pathol. 1975 Apr;28(4):324-31. doi: 10.1136/jcp.28.4.324.
The case histories and blood pictures of two patients who had cardiac lesions, septicaemia, and renal failure and terminally developed a leucoerythroblastic anaemia with megloblastic features associated with multinucleate erythroblasts, are described. Though folate deficiency may have made a minor contribution to the blood abnormalities, it is considered that some other disturbance in erythropoiesis was responsible for the bizarre blood and bone marrow changes in these patients. Similar cases reported in the earlier literature are reviewed.
本文描述了两名患有心脏病变、败血症和肾衰竭的患者的病历及血常规情况，这两名患者最终发展为具有巨幼细胞特征的红系白血病性贫血，并伴有多核幼红细胞。尽管叶酸缺乏可能对血液异常有轻微影响，但据认为，红细胞生成的其他一些紊乱是导致这些患者出现奇异血液和骨髓变化的原因。本文还回顾了早期文献中报道的类似病例。
