Akdis C A, Blaser K
Swiss Institute of Allergy and Asthma Research (SIAF), CH-7270 Davos, Switzerland.
Trends Immunol. 2001 Apr;22(4):175-8. doi: 10.1016/s1471-4906(01)01862-2.
Specific immunotherapy (SIT) is a common treatment for allergic diseases. Despite its usage in clinical practice for nearly a century, more-rational and safer allergen preparations are required. Here, the underlying mechanisms and principles of allergen modification for the future use of SIT in the treatment of allergy are discussed.
特异性免疫疗法（SIT）是治疗过敏性疾病的常用方法。尽管其在临床实践中已使用了近一个世纪，但仍需要更合理、更安全的变应原制剂。在此，我们讨论了变应原修饰的潜在机制和原理，以便未来将SIT用于治疗过敏。
