Kaufman Y, Tzischinsky O, Epstein R, Etzioni A, Lavie P, Pillar G
Sleep Laboratory; Rambam Medical Center and Technion--IIT, Haifa, Israel.
Pediatr Neurol. 2001 Feb;24(2):129-34. doi: 10.1016/s0887-8994(00)00254-x.
It has been demonstrated that patients in the acute phase after minor head injury (MHI) complain of sleep disturbances. The purpose of the present study was to characterize the long-term effects of MHI on sleep in adolescents. Nineteen adolescents who had suffered MHI 3 years before the study and had complained of sleep disturbances completed a sleep questionnaire and were investigated in the sleep laboratory by whole-night polysomnographic recordings and were actigraphically monitored for 5 days at home. Questionnaire results revealed severe complaints regarding sleep behavior. Polysomnographic recordings revealed that in comparison with controls, MHI was associated with lower sleep efficiency (79.8 +/- [9.8]% vs 87.7 +/- [6.8]%; P < 0.005), with more wake time (10.6 +/- [9.0]% vs 3.4 +/- [4.4]%; P < 0.005), and with more awakenings lasting more than 3 minutes (2.1 +/- [1.5] vs 0.6 +/- [0.8]; P < 0.005). These findings were confirmed by actigraphic monitoring that revealed lower sleep efficiency (90 +/- [5]% vs 94 +/- [3]%; P < 0.05), more minutes of wake time (49 +/- [21] min vs 28 +/- [15] min; P < 0.05), and a trend toward more awakenings longer than 5 minutes (1.8 +/- [0.8] vs 1.2 +/- [0.8]; P = 0.063). Our data demonstrated that 3 years after MHI without any discernible clinical sequel, adolescents still complain of sleep disturbances that could be confirmed by both polysomnographic and actigraphic monitoring.
已证实轻度头部损伤（MHI）急性期后的患者会抱怨睡眠障碍。本研究的目的是描述MHI对青少年睡眠的长期影响。19名在研究前3年遭受MHI且抱怨睡眠障碍的青少年完成了一份睡眠问卷，并在睡眠实验室接受了全夜多导睡眠图记录检查，同时在家中进行了为期5天的活动记录仪监测。问卷结果显示，患者对睡眠行为有严重抱怨。多导睡眠图记录显示，与对照组相比，MHI患者的睡眠效率较低（79.8±[9.8]%对87.7±[6.8]%；P<0.005），清醒时间更长（10.6±[9.0]%对3.4±[4.4]%；P<0.005），且持续超过3分钟的觉醒次数更多（2.1±[1.5]对0.6±[0.8]；P<0.005）。活动记录仪监测证实了这些发现，其显示睡眠效率较低（90±[5]%对94±[3]%；P<0.05），清醒时间更长（49±[21]分钟对28±[15]分钟；P<0.05），且持续超过5分钟的觉醒次数有增加趋势（1.8±[0.8]对1.2±[0.8]；P = 0.063）。我们的数据表明，在MHI发生3年后，没有任何明显的临床后遗症，但青少年仍抱怨存在睡眠障碍，这可通过多导睡眠图和活动记录仪监测得到证实。
