Chen K T, Chiou S T, Chang Y C, Pan W H, Twu S J
Centre for Disease Control, Department of Health, Taiwan, Republic of China.
J Int Med Res. 2001 Jan-Feb;29(1):37-40. doi: 10.1177/147323000102900106.
The most common symptoms of chronic beriberi due to thiamine deficiency include dyspnoea, fatigue, leg oedema, lower extremity weakness and numbness. When collapsed peripheral circulation, metabolic acidosis, or shock are present, the disease has advanced from chronic beriberi to pernicious or fulminating beriberi heart failure (Shoshin beriberi). We report two patients with fulminating beriberi; both of whom had been incarcerated at a detention centre for 5 months before hospitalization. A prolonged monotonous diet, low in thiamine, was a major risk factor in both patients. Thiamine deficiency should be considered for any patient with symptoms and signs compatible with beriberi.
由于硫胺素缺乏导致的慢性脚气病最常见的症状包括呼吸困难、疲劳、腿部水肿、下肢无力和麻木。当出现外周循环衰竭、代谢性酸中毒或休克时，疾病已从慢性脚气病进展为恶性或暴发性脚气病心力衰竭（干性脚气病）。我们报告了两名暴发性脚气病患者；两人在住院前均被关押在拘留中心5个月。长期单调的低硫胺素饮食是两名患者的主要危险因素。对于任何有与脚气病相符症状和体征的患者，都应考虑硫胺素缺乏。
