Hüppi P S
Child Development Unit, Department of Pediatrics, University of Geneva, Geneva, Switzerland.
Magn Reson Imaging Clin N Am. 2001 Feb;9(1):1-17, vii.
MR imaging provides an invaluable tool for the study of brain development in vivo. Current MR imaging techniques allow noninvasive methodologies, without ionizing radiation, that provide a diversity of information on structure, metabolism, and function of the developing brain. This article focuses on the application of conventional and advanced MR imaging techniques, including quantitative morphometric MR imaging, diffusion-weighted, functional MR, and MR spectroscopic imaging to the study of early human brain development.
磁共振成像为体内脑发育研究提供了一种非常有价值的工具。当前的磁共振成像技术允许采用非侵入性方法,且无需电离辐射,能够提供有关发育中大脑的结构、代谢和功能的多种信息。本文重点介绍传统和先进的磁共振成像技术,包括定量形态学磁共振成像、扩散加权成像、功能磁共振成像和磁共振波谱成像在早期人类脑发育研究中的应用。