Usui N, Ookoshi H, Mori H, Nozaki M, Saito M, Goto H, Usui M
Department of Ophthalmology, Tokyo Medical University, 6-7-1 Nishi-shinjuku, Shinjuku-ku, Tokyo 160-0023, Japan.
Nippon Ganka Gakkai Zasshi. 2001 Mar;105(3):183-8.
To evaluate the clinical features of nosocomial epidemic keratoconjunctivitis (EKC) occurring in the ophthalmology ward of Tokyo Medical University Hospital.
We studied the symptoms and clinical course of 41 patients who had EKC caused by nosocomial infections in our hospital. We attempted to detect adenovirus antigen and viral DNA from conjunctival swabs and also to isolate the virus.
The clinical symptoms of EKC, including postoperative cases, were not severe. In some cases, patients' complaints, for example, increase of lacrimation or appearance of a foreign body sensation, were contributory to diagnosis. Among the 41 patients, 31 out of 34 (91.2%) EKC patients who had undergone ophthalmic surgery had EKC in the operated eye. In cases receiving bilateral operations, EKC occurred first in the initially operated eye. The sensitivity of Adeno-check was 76.9%. Adenovirus type 19 was isolated from conjunctival swabs in 26 cases.
The early diagnosis of EKC is extremely important to prevent the spread of nosocomial infections. Careful observation of operated eyes and close attention to patient complaints may aid in the early detection of EKC.
评估东京医科大学医院眼科病房发生的医院内流行性角结膜炎（EKC）的临床特征。
我们研究了我院41例因医院感染导致EKC患者的症状和临床病程。我们试图从结膜拭子中检测腺病毒抗原和病毒DNA，并分离病毒。
EKC的临床症状，包括术后病例，并不严重。在某些情况下，患者的主诉，例如流泪增多或出现异物感，有助于诊断。在41例患者中，34例接受眼科手术的EKC患者中有31例（91.2%）患眼为手术眼。在接受双眼手术的病例中，EKC首先发生在最初手术的眼睛。腺病毒检测试剂盒的敏感性为76.9%。从26例结膜拭子中分离出19型腺病毒。
EKC的早期诊断对于预防医院感染的传播极为重要。仔细观察手术眼并密切关注患者主诉可能有助于EKC的早期发现。
