Kumar A, Snyder M
Department of Molecular, Cellular and Developmental Biology, Yale University, PO Box 208103, New Haven, Connecticut 06520-8103, USA.
Nat Rev Genet. 2001 Apr;2(4):302-12. doi: 10.1038/35066084.
The genomic revolution is undeniable: in the past year alone, the term 'genomics' was found in nearly 500 research articles, and at least 6 journals are devoted solely to genomic biology. More than just a buzzword, molecular biology has genuinely embraced genomics (the systematic, large-scale study of genomes and their functions). With its facile genetics, the budding yeast Saccharomyces cerevisiae has emerged as an important model organism in the development of many current genomic methodologies. These techniques have greatly influenced the manner in which biology is studied in yeast and in other organisms. In this review, we summarize the most promising technologies in yeast genomics.
仅在过去一年，“基因组学”一词就出现在近500篇研究论文中，并且至少有6种期刊专门致力于基因组生物学。分子生物学不仅仅是一个流行语，它已经真正地接纳了基因组学（对基因组及其功能进行系统的、大规模的研究）。由于其易于进行遗传学研究，出芽酵母酿酒酵母已成为许多当前基因组方法开发中的重要模式生物。这些技术极大地影响了在酵母和其他生物体中进行生物学研究的方式。在这篇综述中，我们总结了酵母基因组学中最有前景的技术。
