Cruz C, Driemeier D, Pires V S, Schenkel E P
Department of Veterinary Pathology, Federal University of Rio Grande do Sul, Porto Alegre, Brazil.
J Vet Diagn Invest. 2001 Mar;13(2):170-2. doi: 10.1177/104063870101300215.
Cholangiohepatopathy was induced in 5 lambs by oral administration of extracts from signal grass (Brachiaria decumbens) in Brazil. Grossly there were pale foci multifocally distributed throughout the hepatic parenchyma in 4 lambs. The microscopic changes, which were similar to those produced by other steroidal sapogenins-containing plants such as Tribulus terrestris and Panicum spp., included multifocal cholangitis, bile duct proliferation, and the presence of crystals in the biliary system.
在巴西，通过给5只羔羊口服臂形草（俯仰臂形草）提取物诱导出了胆管肝病。大体上，4只羔羊的肝实质内多处出现苍白病灶。显微镜下的变化与其他含甾体皂苷元的植物（如刺蒺藜和黍属植物）所产生的变化相似，包括多灶性胆管炎、胆管增生以及胆道系统中存在晶体。
