Giegé P, Brennicke A
Department of Plant Sciences, Oxford University, South Parks Road, Oxford, OX1 3RB, UK.
C R Acad Sci III. 2001 Mar;324(3):209-17. doi: 10.1016/s0764-4469(00)01293-2.
Higher plant mitochondria contain a genetic system with a genome, transcription and translation processes, which have to be logistically integrated with the two other genomes in the nucleus and the plastid. In plant mitochondria, after transcripts have been synthesised, at least in some cases by a phage-type RNA polymerase, they have to go through a complex processing apparatus, which depends on protein factors imported from the cytosol. Processing involves cis- and trans-splicing, internal RNA editing and maturation at the transcript termini, these steps often occurring in parallel. Transcript life is terminated by RNA degradation mechanisms, one of which involves polyadenylation. RNA metabolism seems to be a key element of the regulation of gene expression in higher plant mitochondria.
高等植物线粒体含有一个具有基因组、转录和翻译过程的遗传系统，该系统在逻辑上必须与细胞核和质体中的另外两个基因组整合。在植物线粒体中，转录本合成后，至少在某些情况下是由噬菌体类型的RNA聚合酶合成的，它们必须经过一个复杂的加工装置，这依赖于从细胞质中导入的蛋白质因子。加工过程包括顺式和反式剪接、内部RNA编辑以及转录本末端的成熟，这些步骤通常同时发生。转录本的寿命通过RNA降解机制终止，其中一种机制涉及多聚腺苷酸化。RNA代谢似乎是高等植物线粒体基因表达调控的关键因素。
