Chung M H, Edinburgh K J, Webb E M, McCowin M, Webb W R
Department of Radiology, Holy Family Hospital, Catholic University of Korea, Kyunggi-Do.
J Thorac Imaging. 2001 Apr;16(2):69-75. doi: 10.1097/00005382-200104000-00001.
Fourteen of 400 consecutive patients having high-resolution computed tomography (HRCT) with expiratory images showed findings of infiltrative lung disease on inspiratory HRCT and air trapping on expiratory CT. Diagnoses included hypersensitivity pneumonitis, sarcoidosis, atypical infection, and pulmonary edema. The extent of infiltrative abnormalities and air trapping were correlated with pulmonary function tests (PFT) in 11 patients. PFT indicated a mixed pattern in five, an obstructive pattern in three, and a restrictive pattern in three. Forced expiratory volume (FEV) in 1 second/forced vital capacity (FVC) correlated significantly with the extent of air-trapping (r = 0.60; p = 0.05). The extent of infiltrative abnormalities correlated significantly and negatively with forced vital capacity (r = -0.82, p = 0.002), FEV1 (r = -0.59, p = 0.05), total lung capacity (TLC) (r = -0.67, p = 0.05), and DLCO (r = -0.75, p = 0.02). Findings of lung infiltration on inspiratory HRCT scans and air trapping on expiratory CT correlated respectively with PFT measures of restrictive and obstructive lung disease.
400例连续接受高分辨率计算机断层扫描（HRCT）并进行呼气期图像扫描的患者中，有14例在吸气期HRCT上显示有浸润性肺疾病表现，在呼气期CT上显示有空气潴留。诊断包括过敏性肺炎、结节病、非典型感染和肺水肿。11例患者的浸润性异常程度和空气潴留程度与肺功能测试（PFT）相关。PFT显示5例为混合模式，3例为阻塞性模式，3例为限制性模式。一秒用力呼气容积（FEV）/用力肺活量（FVC）与空气潴留程度显著相关（r = 0.60；p = 0.05）。浸润性异常程度与用力肺活量（r = -0.82，p = 0.002）、FEV1（r = -0.59，p = 0.05）、肺总量（TLC）（r = -0.67，p = 0.05）和一氧化碳弥散量（DLCO）（r = -0.75，p = 0.02）显著负相关。吸气期HRCT扫描的肺部浸润表现和呼气期CT上的空气潴留分别与限制性和阻塞性肺疾病的PFT指标相关。
