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[瑞典26年来首例狂犬病病例。告知海外旅行者疑似感染后的风险及治疗方法]

[The first case of rabies in Sweden in 26 years. Inform travellers abroad about risks and treatment following suspected infection].

作者信息

Höjer J, Sjöblom E, Berglund O, Hammarin A L, Grandien M

机构信息

Infektionskliniken, Södersjukhuset/Huddinge Universitetssjukhus.

出版信息

Lakartidningen. 2001 Mar 14;98(11):1216-20.

PMID:11293124
Abstract

In June 2000, a case of rabies was diagnosed in Stockholm. The patient, a 19-year-old woman, had been bitten by a dog in Thailand three months earlier. She was admitted with a 2-day history of pain and paresthesia at the exposure site (right arm), along with anxiety. Her neurological symptoms progressed, and during the following week she developed the typical signs of furious rabies. Despite intensive care, her condition deteriorated continuously, and she died 18 days after onset of symptoms. The diagnosis was not considered until five days after admission to the hospital. A saliva sample was obtained and the diagnosis confirmed by virus isolation in mouse neuroblastoma cells. Although Sweden is free of rabies, the diagnosis should be considered in patients with encephalitis after having visited a rabies endemic area. Tourists must be informed of the vital importance of post-exposure prophylaxis after suspected infection.

摘要

2000年6月,斯德哥尔摩确诊了一例狂犬病病例。患者是一名19岁女性,三个月前在泰国被狗咬伤。她因暴露部位(右臂)疼痛和感觉异常2天,并伴有焦虑入院。她的神经症状不断进展,在接下来的一周内出现了狂暴型狂犬病的典型症状。尽管进行了重症监护,她的病情仍持续恶化,症状出现18天后死亡。入院五天后才考虑到诊断。采集了唾液样本,通过在小鼠神经母细胞瘤细胞中进行病毒分离确诊。尽管瑞典没有狂犬病,但对于去过狂犬病流行地区后出现脑炎的患者应考虑进行诊断。必须告知游客疑似感染后暴露后预防的至关重要性。

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