Simon G E, Von Korff M, Rutter C M, Peterson D A
Center for Health Studies, Group Health Cooperative, 1730 Minor Ave, Suite 1600, Seattle, WA 98101-1448, USA.
Arch Gen Psychiatry. 2001 Apr;58(4):395-401. doi: 10.1001/archpsyc.58.4.395.
While many studies describe deficiencies in primary care antidepressant treatment, little research has applied similar standards to psychiatric practice. This study compares baseline characteristics, process of care, and outcomes for managed care patients who received new antidepressant prescriptions from psychiatrists and primary care physicians.
At a prepaid health plan in Washington State, patients receiving initial antidepressant prescriptions from psychiatrists (n = 165) and primary care physicians (n = 204) completed a baseline assessment, including the Structured Clinical Interview for DSM-IV depression module, a 20-item depression assessment from the Symptom Checklist-90, and the Medical Outcomes Survey 36-Item Short-Form Health Survey functional status questionnaire. All measures were repeated after 2 and 6 months. Computerized data were used to assess antidepressant refills and follow-up visits over 6 months.
At baseline, psychiatrists' patients reported slightly higher levels of functional impairment and greater prior use of specialty mental health care. During follow-up, psychiatrists' patients made more frequent follow-up visits, and the proportion making 3 or more visits in 90 days was 57% vs 26% for primary care physicians' patients. The proportion receiving antidepressant medication at an adequate dose for 90 days or more was similar (49% vs 48%). The 2 groups showed similar rates of improvement in all measures of symptom severity and functioning.
In this sample, clinical differences between patients treated by psychiatrists and primary care physicians were modest. Shortcomings in depression treatment frequently noted in primary care (inadequate follow-up care and high rates of inadequate antidepressant treatment) were also common in specialty practice. Possible selection bias limits any conclusions about relative effectiveness or cost-effectiveness.
尽管许多研究描述了初级保健中抗抑郁药物治疗的不足之处,但很少有研究将类似标准应用于精神科实践。本研究比较了从精神科医生和初级保健医生处获得新抗抑郁药物处方的管理式医疗患者的基线特征、护理过程和结局。
在华盛顿州的一个预付健康计划中,从精神科医生(n = 165)和初级保健医生(n = 204)处接受初始抗抑郁药物处方的患者完成了一项基线评估,包括DSM-IV抑郁症模块的结构化临床访谈、症状自评量表90中20项抑郁评估以及医学结局调查36项简短健康调查功能状态问卷。所有测量在2个月和6个月后重复进行。使用计算机化数据评估6个月内的抗抑郁药物续方和随访就诊情况。
在基线时,精神科医生的患者报告的功能损害水平略高,且之前使用专科心理健康护理的频率更高。在随访期间,精神科医生的患者进行随访就诊的频率更高,90天内进行3次或更多次就诊的比例,精神科医生的患者为57%,初级保健医生的患者为26%。接受足够剂量抗抑郁药物90天或更长时间的比例相似(49%对48%)。两组在所有症状严重程度和功能测量指标上的改善率相似。
在本样本中,精神科医生和初级保健医生治疗的患者之间的临床差异不大。初级保健中经常提到的抑郁症治疗缺陷(随访护理不足和抗抑郁药物治疗不足率高)在专科实践中也很常见。可能存在的选择偏倚限制了关于相对有效性或成本效益的任何结论。