Walter E
Arzneimittelforschung. 1978;28(11a):2043-6.
Special problems and possible errors in drug monitoring were discussed by analyzing three cases of hospital treated patients. The first one showed how easily side effects of drug can be falsely diagnosed and treated as a drug independent complicating disease. Furthermore, the active principle of the drug had to be differentiated from several potentially inducing substances. In the second case, the wrong diagnosis of a drug induced illness caused an intermission of a vital basic therapy. The lateron developing signs were interpreted as symptoms of the primary disease but they might also have been caused by drugs given later. For the third case it should be pointed out that side effects can be provoked during long- or short-term treatment by changing the diet. For drug monitoring it is therefore equally necessary to watch the drugs as well as the living circumstances.
通过分析三例医院治疗患者的病例，讨论了药物监测中的特殊问题和可能出现的错误。第一例展示了药物副作用是多么容易被误诊，并被当作与药物无关的并发疾病进行治疗。此外，还必须将药物的活性成分与几种潜在的诱发物质区分开来。在第二例中，药物诱发疾病的错误诊断导致了重要基础治疗的中断。后来出现的症状被解释为原发性疾病的症状，但它们也可能是后来使用的药物引起的。对于第三例，应该指出的是，在长期或短期治疗期间，改变饮食可能会引发副作用。因此，对于药物监测来说，观察药物以及生活环境同样必要。
