Kristiansen B E, Jenkins A, Tveten Y, Karsten B, Line Ø, Bjöersdorff A
AS Telelab Postboks 1868 Gulset 3703 Skien og Avd. for mikrobiologi Universitetet i Tromsø.
Tidsskr Nor Laegeforen. 2001 Mar 10;121(7):805-6.
The bacterium that causes human granulocytic ehrlichiosis may be transmitted by ticks.
We describe two patients with human granulocytic ehrlichiosis. During the summer of 1998, both patients were bitten by ticks. Four to 7 days later they developed influenza-like symptoms with fever, headache and myalgia. After 4 and 21 days, respectively, both patients were given doxycycline for suspected bacterial respiratory diseases, and recovered.
Blood samples for human granulocytic ehrlichiosis antibodies showed a fourfold increase in titer in one patient and a remaining high titer in the other. Both patients had a positive polymerase chain reaction with primers specific for the Ehrlichia phagocytophilae genogroup.
The two patients fulfill the human granulocytic ehrlichiosis diagnostic criteria set by Centers for Disease Controls and Prevention, and are the first two human granulocytic ehrlichiosis cases described in Norway.
引起人类粒细胞埃立克体病的细菌可能通过蜱传播。
我们描述了两名人类粒细胞埃立克体病患者。1998年夏天，两名患者均被蜱叮咬。4至7天后，他们出现了类似流感的症状，包括发热、头痛和肌痛。分别在4天和21天后，两名患者因疑似细菌性呼吸道疾病接受了强力霉素治疗，并康复。
检测人类粒细胞埃立克体病抗体的血样显示，一名患者的滴度增加了四倍，另一名患者的滴度仍保持在高水平。两名患者对嗜吞噬细胞埃立克体基因组特异性引物的聚合酶链反应均呈阳性。
这两名患者符合美国疾病控制与预防中心设定的人类粒细胞埃立克体病诊断标准，是挪威描述的首例两例人类粒细胞埃立克体病病例。
