Christensen M F, Mortensen O
Arch Dis Child. 1975 Feb;50(2):110-4. doi: 10.1136/adc.50.2.110.
The present study is a follow-up of 34 cases admitted to a paediatric department with recurrent abdominal pain (RAP) in 1942 and 1943. 45 persons without a history of RAP were selected at random and included as controls. Using a questionnaire, there was a higher incidence of gastrointestinal symptoms among persons with a history of RAP during childhood than among controls (P less than 0.05). 18 of the original 34 cases who still had symptoms were re-examined; 11 had a clinical picture consistent with a diagnosis of irritable colon, 5 had a picture compatible with both irritable colon and peptic ulcer/gastritis, and 2 had duodenal ulcer. Abdominal pains occurred no more frequently among children of parents who had had RAP during childhood than among children of parents without such a history. However, there was a higher incidence of abdominal pain among children of parents who were complaining of abdominal discomfort at the time of the investigation than among children whose parents were without such symptoms (P less than 0.005).
本研究是对1942年和1943年收治于儿科的34例复发性腹痛(RAP)病例的随访。随机选取45例无RAP病史者作为对照。通过问卷调查发现,有童年RAP病史者的胃肠道症状发生率高于对照组(P<0.05)。对最初34例仍有症状的病例中的18例进行了复查;11例临床表现符合肠易激综合征诊断,5例符合肠易激综合征合并消化性溃疡/胃炎表现,2例有十二指肠溃疡。父母有童年RAP病史的儿童腹痛发作频率并不高于父母无此病史的儿童。然而,在调查时父母主诉腹部不适的儿童中,腹痛发生率高于父母无此类症状的儿童(P<0.005)。