Thompson W G
Gut. 1984 Oct;25(10):1089-92. doi: 10.1136/gut.25.10.1089.
Symptoms of 50 patients with the irritable bowel syndrome were compared with those of 49 with endoscopically proven peptic ulcer disease and 49 with radiologically or endoscopically proven inflammatory bowel disease using a questionnaire which was administered after the diagnosis was made. Symptoms of bowel dysfunction including pain related to bowel movements were more likely to occur in the irritable bowel syndrome than peptic ulcer disease. Only abdominal distension, straining at stool and scybala, however, were significantly more likely in the irritable bowel syndrome than inflammatory bowel disease. Four symptoms previously shown to be more common in irritable bowel syndrome than in organic abdominal disease were combined. The more of these symptoms that were present, the more likely were the patients to have the irritable bowel syndrome than peptic ulcer disease. Symptoms of gut dysfunction are highly discriminating between irritable bowel syndrome and peptic ulcer disease but less so between irritable bowel syndrome and inflammatory bowel disease.
采用一份在确诊后发放的问卷，对50例肠易激综合征患者的症状与49例经内镜证实的消化性溃疡病患者以及49例经放射学或内镜证实的炎性肠病患者的症状进行了比较。与排便相关的疼痛等肠功能障碍症状在肠易激综合征患者中比消化性溃疡病患者更易出现。然而，只有腹胀、排便时用力和粪块在肠易激综合征患者中比炎性肠病患者明显更常见。将先前显示在肠易激综合征中比在器质性腹部疾病中更常见的四种症状合并起来。这些症状出现得越多，与消化性溃疡病相比，患者患肠易激综合征的可能性就越大。肠道功能障碍症状在肠易激综合征和消化性溃疡病之间具有高度鉴别性，但在肠易激综合征和炎性肠病之间的鉴别性较小。
