Campbell D P, Smith E I, Bhatia M, Poley J R, Williams G R
Ann Surg. 1975 May;181(5):591-5. doi: 10.1097/00000658-197505000-00012.
A series of 12 infants undergoing hepatic portoenterostomy for incorrectable-type biliary atresia is reviewed. There has been no evidence of a sustained postoperative increase in bile excretion or improvement in biliary cirrhosis in any patient. Survival statistics for the group as a whole are poor with a mean postop survival time of 11 months and a mean total survival time of 15.3 months. These survival times are worse than that previously reported for infants with untreated biliary atresia. Our disappointing results with hepatic portoenterostomy raise doubts concerning its value in the treatment of biliary atresia.
回顾了一系列12例因不可矫正型胆道闭锁而接受肝门肠吻合术的婴儿。没有证据表明任何患者术后胆汁排泄持续增加或胆汁性肝硬化有所改善。该组整体生存统计数据不佳,术后平均生存时间为11个月,平均总生存时间为15.3个月。这些生存时间比之前报道的未经治疗的胆道闭锁婴儿的生存时间更差。我们在肝门肠吻合术上令人失望的结果引发了对其在胆道闭锁治疗中价值的质疑。