El Danasoury M A, El Maghraby A, Coorpender S J
Magrabi Eye Center, Abu Dhabi, United Arab Emirates.
J Refract Surg. 2001 Mar-Apr;17(2):97-104. doi: 10.3928/1081-597X-20010301-01.
To study the change in the intraocular pressure (IOP) after laser in situ keratomileusis (LASIK) for correction of myopia.
One hundred twenty consecutive myopic eyes (60 patients) were included in a prospective study. All eyes received LASIK with the Nidek EC-5000 excimer laser and the Chiron Automated Corneal Shaper. Baseline refraction, keratometry, pachymetry, ablation depth, and IOP measured by Goldmann applanation tonometry and non-contact air puff tonometry were correlated with the IOP change after surgery. Sixty healthy eyes of 30 subjects served as controls.
At 6 months, 108 eyes (90%) were examined. Compared to preoperative values, IOP decreased in 103 eyes (95.4%) when measured with applanation tonometry; it decreased in all eyes when measured with air puff tonometry. Mean change in IOP was -4.3 +/- 2.1 mmHg (range, -10.0 to +1.0 mmHg) with the applanation and -6.1 +/- 2.3 mmHg (range, -12.0 to -1.0 mmHg) with air puff tonometry. The IOP change measured with either instrument correlated significantly with the baseline IOP (P < .001) and the ablation depth (air puff, P < .001, applanation; P = .006).
Intraocular pressure decreased significantly after LASIK when measured with either Goldmann (mean 4.3 mmHg) or air puff (mean 6.1 mmHg) tonometers. This decrease may delay the diagnosis or affect the management of future glaucoma that may develop in a myopic eye that received LASIK.
研究准分子原位角膜磨镶术(LASIK)矫正近视后眼内压(IOP)的变化。
120只连续的近视眼睛(60例患者)纳入一项前瞻性研究。所有眼睛均使用Nidek EC - 5000准分子激光和Chiron自动角膜板层成形系统进行LASIK手术。通过Goldmann压平眼压计和非接触式气眼压计测量的基线屈光、角膜曲率、角膜厚度、消融深度和IOP与术后IOP变化相关。30名受试者的60只健康眼睛作为对照。
6个月时,检查了108只眼睛(90%)。与术前值相比,用压平眼压计测量时,103只眼睛(95.4%)的IOP下降;用气眼压计测量时,所有眼睛的IOP均下降。压平眼压计测量的IOP平均变化为 -4.3±2.1 mmHg(范围,-10.0至+1.0 mmHg),气眼压计测量的为 -6.1±2.3 mmHg(范围,-12.0至 -1.0 mmHg)。用任何一种仪器测量的IOP变化均与基线IOP(P <.001)和消融深度显著相关(气眼压计,P <.001,压平眼压计;P =.006)。
用Goldmann(平均4.3 mmHg)或气眼压计(平均6.1 mmHg)测量时,LASIK术后眼内压显著下降。这种下降可能会延迟诊断或影响接受LASIK手术的近视眼未来可能发生的青光眼的治疗。