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持续气道正压通气(CPAP)治疗睡眠呼吸暂停第一晚后的慢波睡眠反弹和快速眼动睡眠反弹:与睡眠质量主观改善的相关性

Slow wave sleep rebound and REM rebound following the first night of treatment with CPAP for sleep apnea: correlation with subjective improvement in sleep quality.

作者信息

Verma A, Radtke R A., VanLandingham K E., King J H., Husain A M.

机构信息

Section of Clinical Neurophysiology, Department of Neurology, Baylor College of Medicine, TX 77030, Houston, USA

出版信息

Sleep Med. 2001 May;2(3):215-223. doi: 10.1016/s1389-9457(00)00069-1.

DOI:10.1016/s1389-9457(00)00069-1
PMID:11311684
Abstract

Objective: The purpose of this study was to correlate changes in PSG parameters between the diagnostic polysomnogram (dPSG) and the first night of treatment with continuous positive airway pressure (CPAP) (cpapPSG) to subjective improvement in sleep quality.Background: In patients with obstructive sleep apnea syndrome (OSAS), therapy with CPAP results in reduction of sleep latency, stage 1 sleep, arousal index (Al) and respiratory disturbance index (RDI), and increase in stage 2 sleep, REM sleep and REM density. No data exists on the differences in polysomnographic (PSG) parameters in patients who have subjective improvement in sleep quality and those who do not.Methods: We retrospectively reviewed PSG studies of 44 patients with OSAS who presented to the Sleep Disorders Center at Duke University Medical Center. Patient's qualitative assessment of sleep was noted using a Likert-type scale administered the morning after the dPSG and cpapPSG. PSG indices of patients noting subjective improvement were compared to those with no improvement.Results: Patients noting a subjective improvement in sleep quality showed a decrease in the percentages of stage 1 sleep (P<0.001) and an increase in percentages of stages 3 and 4 sleep (slow wave sleep rebound; P<0.007) and stage REM sleep (REM rebound; P<0.008).

摘要

目的

本研究旨在将诊断性多导睡眠图(dPSG)与持续气道正压通气(CPAP)治疗第一晚的多导睡眠图(cpapPSG)参数变化与睡眠质量的主观改善相关联。背景:在阻塞性睡眠呼吸暂停综合征(OSAS)患者中,CPAP治疗可导致睡眠潜伏期、1期睡眠、觉醒指数(Al)和呼吸紊乱指数(RDI)降低,2期睡眠、快速眼动(REM)睡眠和REM密度增加。对于睡眠质量有主观改善的患者和没有主观改善的患者,多导睡眠图(PSG)参数的差异尚无数据。方法:我们回顾性分析了44例就诊于杜克大学医学中心睡眠障碍中心的OSAS患者的PSG研究。在dPSG和cpapPSG后的早晨,使用李克特量表记录患者对睡眠的定性评估。将记录到主观改善的患者的PSG指标与没有改善的患者的PSG指标进行比较。结果:睡眠质量有主观改善的患者显示1期睡眠百分比降低(P<0.001),3期和4期睡眠(慢波睡眠反弹;P<0.007)以及REM睡眠(REM反弹;P<0.008)百分比增加。

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