Pantridge J F, Adgey A A, Webb S W, Anderson J
Br Med J. 1975 May 10;2(5966):313-5. doi: 10.1136/bmj.2.5966.313.
Most deaths from ischaemic heart disease are sudden, occur outside hospital, and result from ventricular fibrillation. But defibrillators have only limited availability because of their size and weight. A miniature defibrillator has been developed. A singe low-energy shock succeeded in removing ventricular fibrillation in 73 out of 82 episodes, and a further shock was successful in seven more episodes. Primary ventricular fibrillation probably always responds to low-energy electrical shocks, which challenges the conventional view that correction of ventricular fibrillation requires high-energy direct-current shock. Thus even smaller and lighter defibrillators are possible. Furthermore low-energy shocks cause less myocardial damage.
大多数缺血性心脏病导致的死亡是突然发生的,在院外发生,且由心室颤动所致。但除颤器由于其尺寸和重量,可用性有限。一种微型除颤器已被研发出来。单次低能量电击成功消除了82次发作中的73次心室颤动,再一次电击又成功消除了另外7次发作。原发性心室颤动可能总是对低能量电击有反应,这对心室颤动的纠正需要高能量直流电电击的传统观点提出了挑战。因此,甚至更小、更轻的除颤器也是有可能的。此外,低能量电击造成的心肌损伤更小。