Institute of Health Care Engineering with European Testing Center of Medical Devices, Graz University of Technology, A-8010 Graz, Austria.
Clinical Division of Pediatric Cardiology, Department of Pediatrics and Adolescent Medicine, Medical University of Graz, A-8036 Graz, Austria.
Sensors (Basel). 2022 Apr 6;22(7):2808. doi: 10.3390/s22072808.
For cardiac defibrillator testing and design purposes, the range and limits of the human TTI is of high interest. Potential influencing factors regarding the electronic configurations, the electrode/tissue interface and patient characteristics were identified and analyzed. A literature survey based on 71 selected articles was used to review and assess human TTI and the influencing factors found. The human TTI extended from 12 to 212 Ω in the literature selected. Excluding outliers and pediatric measurements, the mean TTI recordings ranged from 51 to 112 Ω with an average TTI of 76.7 Ω under normal distribution. The wide range of human impedance can be attributed to 12 different influencing factors, including shock waveforms and protocols, coupling devices, electrode size and pressure, electrode position, patient age, gender, body dimensions, respiration and lung volume, blood hemoglobin saturation and different pathologies. The coupling device, electrode size and electrode pressure have the greatest influence on TTI.
出于心脏除颤器测试和设计的目的,人体 TTI 的范围和极限是非常重要的。确定并分析了与电子配置、电极/组织界面和患者特征有关的潜在影响因素。基于 71 篇选定文章的文献综述用于回顾和评估人体 TTI 以及发现的影响因素。在所选文献中,人体 TTI 从 12 到 212 Ω 不等。排除异常值和儿科测量值,正常分布下的 TTI 记录平均值在 51 到 112 Ω 之间,平均 TTI 为 76.7 Ω。人体阻抗的广泛范围可归因于 12 个不同的影响因素,包括电击波形和协议、耦合设备、电极尺寸和压力、电极位置、患者年龄、性别、体型、呼吸和肺活量、血液血红蛋白饱和度和不同的病理状况。耦合设备、电极尺寸和电极压力对 TTI 的影响最大。