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泰国东北部孔敬地区学童哮喘、过敏性鼻炎和湿疹患病率调查。一项国际儿童哮喘和过敏研究(ISAAC研究)

Survey of the prevalence of asthma, allergic rhinitis and eczema in schoolchildren from Khon Kaen, Northeast Thailand. an ISAAC study. International Study of Asthma and Allergies in Childhood.

作者信息

Teeratakulpisarn J, Pairojkul S, Heng S

机构信息

Department of Pediatrics, Faculty of Medicine, Khon Kaen University, Thailand.

出版信息

Asian Pac J Allergy Immunol. 2000 Dec;18(4):187-94.

Abstract

This survey of schoolchildren from Khon Kaen, Northeast Thailand used the standardized ISAAC questionnaires to estimate the prevalence of asthma and other allergic diseases and to compare the results with two previous studies. A total of 6,068 questionnaires were analyzed (2,658, 45.6% males from the 6 to 7 years old group and 3,410, 49.5% male from the 13 to 14 years old group). The three predominant cumulative and 12-month conditions discerned from the written questionnaires among the 6 to 7 vs 13 to 14 years old were: wheezing, at 18.6% and 10.2% vs 20.5% and 11.0%; rhinitis at 38.4% and 33.5% vs 59.4% and 42.5%; and eczema at 18.0% and 15.2% vs 9.9% and 7.4%, respectively. The observed prevalences in our study were similar to those found in Bangkok and slightly higher than those in Chiang Mai, except for 'exercise wheezing' in older children which was two times higher in our study than in the two previous studies. Our study showed seasonal variation of the 'nose' symptoms. The peak prevalence was in the relatively cool and dry season (between November and January), which was the same pattern as Chiang Mai but different from Bangkok (which had a perennial pattern and less climatic variation). Our results concurred with the two previous Thai ISAAC studies. There is a high prevalence of asthma and other allergic diseases among Thai children and there has been a four-fold increase in symptoms since the last decade. If the trend persists asthma and allergic disease may become a pressing health concern of the country.

摘要

这项针对泰国东北部孔敬府学童的调查使用标准化的国际儿童哮喘和过敏症研究(ISAAC)问卷来估计哮喘及其他过敏性疾病的患病率,并将结果与此前的两项研究进行比较。总共分析了6068份问卷(6至7岁组中有2658份,男性占45.6%;13至14岁组中有3410份,男性占49.5%)。在6至7岁与13至14岁儿童的书面问卷中识别出的三种主要的累积病症和12个月内出现的病症分别为:喘息,6至7岁组中患病率为18.6%和10.2%,13至14岁组中为20.5%和11.0%;鼻炎,6至7岁组中患病率为38.4%和33.5%,13至14岁组中为59.4%和42.5%;湿疹,6至7岁组中患病率为18.0%和15.2%,13至14岁组中为9.9%和7.4%。我们研究中观察到的患病率与曼谷的患病率相似,略高于清迈的患病率,但在年长儿童中的“运动性喘息”情况除外,我们研究中的患病率比此前两项研究高出两倍。我们的研究显示了“鼻部”症状的季节性变化。患病率高峰出现在相对凉爽干燥的季节(11月至1月之间),这与清迈的模式相同,但与曼谷不同(曼谷呈现常年发病模式,气候差异较小)。我们的结果与此前两项泰国ISAAC研究一致。泰国儿童中哮喘和其他过敏性疾病的患病率很高,自上一个十年以来症状增加了四倍。如果这种趋势持续下去,哮喘和过敏性疾病可能会成为该国紧迫的健康问题。

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