Grossman E, Grossman A, Schein M H, Zimlichman R, Gavish B
Internal Medicine D, The Chaim Sheba Medical Center, Tel-Hashomer, Israel.
J Hum Hypertens. 2001 Apr;15(4):263-9. doi: 10.1038/sj.jhh.1001147.
We hypothesise that routinely applied short sessions of slow and regular breathing can lower blood pressure (BP). Using a new technology BIM (Breathe with Interactive Music), hypertensive patients were guided towards slow and regular breathing. The present study evaluates the efficacy of the BIM in lowering BP. We studied 33 patients (23M/10F), aged 25-75 years, with uncontrolled BP. Patients were randomised into either active treatment with the BIM (n = 18) or a control treatment with a Walkman (n = 15). Treatment at home included either musically-guided breathing exercises with the BIM or listening to quiet music played by a Walkman for 10 min daily for 8 weeks. BP and heart rate were measured both at the clinic and at home with an Omron IC BP monitor. Clinic BP levels were measured at baseline, and after 4 and 8 weeks of treatment. Home BP measurements were taken daily, morning and evening, throughout the study. The two groups were matched by initial BP, age, gender, body mass index and medication status. The BP change at the clinic was -7.5/-4.0 mm Hg in the active treatment group, vs -2.9/-1.5 mm Hg in the control group (P = 0.001 for systolic BP). Analysis of home-measured data showed an average BP change of -5.0/-2.7 mm Hg in the active treatment group and -1.2/+0.9 mm Hg in the control group. Ten out of 18 (56%) were defined as responders in the active treatment group but only two out of 14 (14%) in the control group (P = 0.02). Thus, breathing exercise guided by the BIM device for 10 min daily is an effective non-pharmacological modality to reduce BP.
我们假设，常规进行的短时间、缓慢且规律的呼吸能够降低血压（BP）。利用一项名为BIM（交互式音乐呼吸法）的新技术，引导高血压患者进行缓慢且规律的呼吸。本研究评估了BIM在降低血压方面的疗效。我们研究了33例患者（23例男性/10例女性），年龄在25至75岁之间，血压控制不佳。患者被随机分为接受BIM主动治疗组（n = 18）或使用随身听的对照组（n = 15）。在家治疗包括使用BIM进行音乐引导的呼吸练习，或每天听随身听播放的安静音乐10分钟，持续8周。使用欧姆龙IC血压监测仪在诊所和家中测量血压和心率。在基线时以及治疗4周和8周后测量诊所血压水平。在整个研究过程中，每天早晚在家中测量血压。两组在初始血压、年龄、性别、体重指数和用药状况方面进行了匹配。主动治疗组诊所血压的变化为-7.5/-4.0毫米汞柱，而对照组为-2.9/-1.5毫米汞柱（收缩压P = 0.001）。对家庭测量数据的分析显示，主动治疗组平均血压变化为-5.0/-2.7毫米汞柱，对照组为-1.2/+0.9毫米汞柱。主动治疗组18例中有10例（56%）被定义为反应者，而对照组14例中只有2例（14%）（P = 0.02）。因此，每天使用BIM设备引导呼吸练习10分钟是一种有效的非药物降压方法。
