Meles Ester, Giannattasio Cristina, Failla Monica, Gentile Gaetano, Capra Anna, Mancia Giuseppe
Clinica Medica, Dipartimento di Medicina Clinica, Prevenzione e Biotecnologie Sanitarie, Università degli Studi di Milano-Bicocca, S. Gerardo Hospital Monza, Italy.
Am J Hypertens. 2004 Apr;17(4):370-4. doi: 10.1016/j.amjhyper.2003.12.009.
Device-guided breathing exercises at home have a potential to become a nonpharmacologic treatment of high blood pressure (BP). The aim of this study was to evaluate the impact of device-guided breathing exercises on both office and home BP.
A total of 79 mild hypertensive individuals, either medicated or unmedicated, with BP > 140/90 mm Hg were enrolled. After a 2-week run-in phase, in both the control and treatment groups daily home blood pressure was monitored for 8 weeks. The treatment group also engaged in 15-min daily sessions with device-guided breathing exercises.
A total of 47 treatment patients and 26 control subjects completed the study. In the control group both office and home BP showed small nonsignificant reductions. Device-guided breathing exercises reduced mean office BP (systolic/diastolic) by 5.5/3.6 mm Hg (P < .05 for diastolic) and mean home BP by 5.4/3.2 mm Hg (P < .001 for both). Home BP response reached a plateau after 3 weeks.
Our data show that device-guided breathing exercises have an antihypertensive effect that can be seen in conditions closer to daily life than the setting of the physician's office.
在家中进行设备引导的呼吸练习有可能成为高血压的一种非药物治疗方法。本研究的目的是评估设备引导的呼吸练习对诊室血压和家庭血压的影响。
共纳入79名轻度高血压患者，无论是否用药，血压>140/90 mmHg。在为期2周的导入期后，对照组和治疗组均进行为期8周的家庭血压监测。治疗组还每天进行15分钟的设备引导呼吸练习。
共有47名治疗患者和26名对照受试者完成了研究。对照组的诊室血压和家庭血压均有小幅但无显著意义的下降。设备引导的呼吸练习使诊室平均血压（收缩压/舒张压）降低了5.5/3.6 mmHg（舒张压P<.05），家庭平均血压降低了5.4/3.2 mmHg（两者P<.001）。家庭血压反应在3周后达到平稳状态。
我们的数据表明，设备引导的呼吸练习具有降压作用，在比诊室环境更接近日常生活的情况下即可观察到。
