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播散性浅表性光化性汗孔角化症,兼具典型病变和痒疹结节样病变。

Disseminated superficial actinic porokeratosis with both typical and prurigo nodularis-like lesions.

作者信息

Kang B D, Kye Y C, Kim S N

机构信息

Department of Dermatology, Anam Hospital of Korea University Medical Center, 126-1, 5-ka, Anam-dong, Seongbuk-ku, Seoul, 136-705, Korea.

出版信息

J Dermatol. 2001 Feb;28(2):81-5. doi: 10.1111/j.1346-8138.2001.tb00094.x.

Abstract

We report a 50-year-old Korean patient who developed a disseminated superficial actinic porokeratosis (DSAP) with two types of lesions. One was a typical DSAP lesion clinically and histopathologically. The other was clinically similar to prurigo nodularis, but histologic examination showed the findings of porokeratosis such as cornoid lamellae and loss of the granular layer in addition to those of chronic lichenified dermatitis, so it could be described as prurigo nodularis-like porokeratosis. The nodular lesions seemed to develop on preexisting typical lesions of DSAP mainly during the summer by the aggravation of pruritic symptoms and scratching associated with sun exposure. Although we could not find any published reports describing lesions like those of our case, we think that such prurigo nodularis-like porokeratosis can develop in patients with DSAP in some situations involving pruritus and scratching.

摘要

我们报告了一名50岁的韩国患者,其患有伴有两种皮损类型的播散性浅表性光化性汗孔角化症(DSAP)。一种在临床和组织病理学上是典型的DSAP皮损。另一种在临床上类似于结节性痒疹,但组织学检查除了显示慢性苔藓化性皮炎的表现外,还呈现出汗孔角化症的特征,如鸡眼样板层和颗粒层缺失,因此可将其描述为结节性痒疹样汗孔角化症。结节性皮损似乎主要在夏季,由于瘙痒症状加重以及与日晒相关的搔抓,在已存在的典型DSAP皮损基础上发展而来。尽管我们未找到任何已发表的报告描述与我们病例类似的皮损,但我们认为在某些涉及瘙痒和搔抓的情况下,DSAP患者可能会出现这种结节性痒疹样汗孔角化症。

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