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色素播散性浅表性光化性汗孔角化症的临床和皮肤镜特征:病例报告及文献复习。

Clinical and Dermoscopic Features of Pigmented Disseminated Superficial Actinic Porokeratosis: Case Report and Literature Review.

机构信息

1 Division of Dermatology, Department of Medicine, University of Alberta, Edmonton, AB, Canada.

2 Department of Laboratory Medicine and Pathology, University of Alberta, Edmonton, AB, Canada.

出版信息

J Cutan Med Surg. 2018 Mar/Apr;22(2):229-231. doi: 10.1177/1203475417733465. Epub 2017 Sep 18.

DOI:10.1177/1203475417733465
PMID:28922948
Abstract

INTRODUCTION

Porokeratosis is a benign hyperkeratotic skin tumour due to a clonal proliferation of keratinocytes and is characterised by a telltale annular threadlike configuration along the border of a skin-colored to erythematous papule that can expand centrifugally.

CASE PRESENTATION

We are presenting a clinical and dermoscopic case of pigmented disseminated superficial actinic porokeratosis (DSAP) limited to the upper trunk of a white man with sun-damaged skin. Literature Review and Conclusion: A thorough review of PubMed failed to identify any previous reports on the dermoscopic appearance of pigmented porokeratosis. On dermoscopy, the presence of black dots limited to the periphery of the lesions is due to pigment incontinence and melanophages within the superficial papillary dermis limited to the area below the cornoid lamella. Pigmented DSAP is a unique morphological presentation of porokeratosis, and it is essential to be familiar with its clinical and dermoscopic presentation.

摘要

简介

角化病是一种良性角化过度性皮肤肿瘤,是由于角朊细胞的克隆性增殖引起的,其特征是在皮肤色至红斑性丘疹的边缘沿著典型的环形线状结构,可向心性扩大。

病例介绍

我们呈现了一个临床和皮肤镜下的色素性播散性浅表光化性角化病(DSAP)的病例,局限于一个白人男性的上躯干,该男性有日光损伤的皮肤。文献回顾和结论:对 PubMed 的全面回顾未能发现任何关于色素性角化病皮肤镜表现的先前报告。在皮肤镜下,局限于病变周边的黑色小点是由于色素失禁和位于颗粒层下方的浅层乳头状真皮内的噬黑素细胞。色素性 DSAP 是角化病的一种独特形态表现,熟悉其临床和皮肤镜表现至关重要。

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