使用微悬臂梁传感器对铬酸根离子（CrO4(2-)）进行超灵敏检测。

Ultrasensitive detection of CrO4(2-) using a microcantilever sensor.

作者信息

Ji H F, Thundat T, Dabestani R, Brown G M, Britt P F, Bonnesen P V

机构信息

Chemical and Analytical Sciences Division, Oak Ridge National Laboratory, Tennessee 37831, USA.

出版信息

Anal Chem. 2001 Apr 1;73(7):1572-6. doi: 10.1021/ac0013103.

DOI:10.1021/ac0013103

PMID:11321311

Abstract

Microcantilevers modified with a self-assembled monolayer respond sensitively to specific ion concentrations. Here, we report the detection of trace amounts of CrO4(2-) using microcantilevers modified with a self-assembled monolayer of triethyl-12-mercaptododecylammonium bromide. The self-assembled monolayer was prepared on a silicon microcantilever coated with a thin layer of gold on one side. The microcantilever undergoes bending due to sorption of CrO4(2-) ions on the monolayer-modified side. It was found that a concentration of 10(-9) M CrO4(2-) can be detected using this technology in a flow cell. Other anions, such as Cl-, Br-, CO3(2-) (or HCO3-), and SO4(2-), have minimal effect on the deflection of this cantilever. The mechanics of the bending and the chemistry of cantilever modification are discussed.

摘要

用自组装单分子层修饰的微悬臂梁对特定离子浓度有灵敏响应。在此，我们报告了使用用溴化三乙基 - 12 - 巯基十二烷基铵自组装单分子层修饰的微悬臂梁来检测痕量的CrO4(2-)。自组装单分子层是在一侧涂有薄层金的硅微悬臂梁上制备的。由于CrO4(2-)离子吸附在单分子层修饰的一侧，微悬臂梁会发生弯曲。结果发现，使用该技术在流通池中可以检测到浓度为10(-9) M的CrO4(2-)。其他阴离子，如Cl-、Br-、CO3(2-)(或HCO3-)和SO4(2-)，对该悬臂梁的偏转影响极小。本文讨论了弯曲的力学原理以及悬臂梁修饰的化学过程。