Xu Xiaohe, Thundat Thomas G, Brown Gilbert M, Ji Hai-Feng
Chemistry Program Institute for Micromanufacturing, Louisiana Tech University, Ruston 71272, USA.
Anal Chem. 2002 Aug 1;74(15):3611-5. doi: 10.1021/ac0255781.
Trace amounts of Hg2+ are detected by using a microcantilever coated with gold. The microcantilever undergoes bending due to accumulation of Hg2+ on the gold surface. It is found that a concentration of 10(-11) M Hg2+ can be detected using this technology. Other cations, such as K+, Na+, Pb2+, Zn2+, Ni2, Cd2+, Cu2+, and Ca2+ have little or no effect on the deflection of the cantilever. The selectivity of the Hg2+ sensor could be improved by coating the gold surface of microcantilever with a self-assembled monolayer of a long-chain thiol compound.
通过使用涂有金的微悬臂梁来检测痕量的Hg2+。由于Hg2+在金表面的积累，微悬臂梁会发生弯曲。发现使用该技术可以检测到浓度为10(-11) M的Hg2+。其他阳离子，如K+、Na+、Pb2+、Zn2+、Ni2、Cd2+、Cu2+和Ca2+对悬臂梁的偏转影响很小或没有影响。通过用长链硫醇化合物的自组装单分子层涂覆微悬臂梁的金表面，可以提高Hg2+传感器的选择性。
