Rondón P, Aguilar A, Gallego M
Servicio de Medicina Interna, Hospital Severo Ochoa, Leganés, Madrid.
An Med Interna. 2001 Feb;18(2):88-9.
Two patients are reported with localized scleroderma who developed thrombocytopenia. One of these patients had a positive antinuclear antibody (ANA) and Anti-DNA antibodies tests. The occurrence of thrombocytopenia in localized scleroderma suggests an autoimmune mechanism, by the response to steroids and the presence of positive autoantibodies. This possible association emphasizes the need to look for hematologic disorders in patients with systemic, as well as localized scleroderma.
报告了两名局限性硬皮病患者出现血小板减少症。其中一名患者抗核抗体（ANA）和抗DNA抗体检测呈阳性。局限性硬皮病中血小板减少症的发生提示存在自身免疫机制，依据对类固醇的反应以及自身抗体阳性的情况。这种可能的关联强调了在系统性和局限性硬皮病患者中寻找血液系统疾病的必要性。
