Sempau J, Sánchez-Reyes A, Salvat F, ben Tahar H O, Jiang S B, Fernández-Varea J M
Institut de Tècniques Energètiques, Universitat Politècnica de Catalunya, Barcelona, Spain.
Phys Med Biol. 2001 Apr;46(4):1163-86. doi: 10.1088/0031-9155/46/4/318.
The Monte Carlo code PENELOPE has been used to simulate electron beams from a Siemens Mevatron KDS linac with nominal energies of 6, 12 and 18 MeV. Owing to its accuracy, which stems from that of the underlying physical interaction models, PENELOPE is suitable for simulating problems of interest to the medical physics community. It includes a geometry package that allows the definition of complex quadric geometries, such as those of irradiation instruments, in a straightforward manner. Dose distributions in water simulated with PENELOPE agree well with experimental measurements using a silicon detector and a monitoring ionization chamber. Insertion of a lead slab in the incident beam at the surface of the water phantom produces sharp variations in the dose distributions, which are correctly reproduced by the simulation code. Results from PENELOPE are also compared with those of equivalent simulations with the EGS4-based user codes BEAM and DOSXYZ. Angular and energy distributions of electrons and photons in the phase-space plane (at the downstream end of the applicator) obtained from both simulation codes are similar, although significant differences do appear in some cases. These differences, however, are shown to have a negligible effect on the calculated dose distributions. Various practical aspects of the simulations, such as the calculation of statistical uncertainties and the effect of the 'latent' variance in the phase-space file, are discussed in detail.
蒙特卡罗代码PENELOPE已被用于模拟西门子Mevatron KDS直线加速器产生的标称能量为6、12和18兆电子伏的电子束。由于其准确性源于基础物理相互作用模型的准确性,PENELOPE适用于模拟医学物理领域感兴趣的问题。它包括一个几何包,能以直接的方式定义复杂的二次几何形状,如辐照仪器的几何形状。用PENELOPE模拟的水中剂量分布与使用硅探测器和监测电离室的实验测量结果吻合良好。在水体模表面的入射束中插入一块铅板会使剂量分布产生急剧变化,模拟代码能正确再现这种变化。PENELOPE的结果也与基于EGS4的用户代码BEAM和DOSXYZ的等效模拟结果进行了比较。从两个模拟代码获得的相空间平面(在施源器下游端)中电子和光子的角度和能量分布相似,尽管在某些情况下确实存在显著差异。然而,这些差异对计算出的剂量分布的影响可忽略不计。详细讨论了模拟的各种实际问题,如统计不确定性的计算和相空间文件中“潜在”方差的影响。