Ulubelen A, Oksüz S, Topcu G, Gören A C, Voelter W
Department of Chemistry, Faculty of Pharmacy, University of Istanbul, 34452 Istanbul, Turkey.
J Nat Prod. 2001 Apr;64(4):549-51. doi: 10.1021/np0004956.
The roots of Salvia blepharochlaena have yielded two new diterpenoids, blephaein (1) and O-methylpisiferic acid methyl ester (2), together with eight known diterpenoids. The structures of the new compounds were established by spectroscopic analysis and by some chemical reactions. Potent antibacterial activity was exhibited by the known compounds horminone (9) and 7-acetylhorminone (10) against Staphylococcus aureus ATCC 6538 P, Staphylococcus epidermidis ATCC 12226, and Bacillus subtilis ATCC 6633. Horminone was also found to be active against Enterococcus faecalis ATCC 29212.
鼠尾草（Salvia blepharochlaena）的根产生了两种新的二萜类化合物，鼠尾草素（1）和O - 甲基松叶菊酸甲酯（2），以及八种已知的二萜类化合物。通过光谱分析和一些化学反应确定了新化合物的结构。已知化合物荷米酮（9）和7 - 乙酰荷米酮（10）对金黄色葡萄球菌ATCC 6538 P、表皮葡萄球菌ATCC 12226和枯草芽孢杆菌ATCC 6633表现出强效抗菌活性。还发现荷米酮对粪肠球菌ATCC 29212有活性。
