Dusenbery D B, Sheridan R E, Russell R L
Genetics. 1975 Jun;80(2):297-309. doi: 10.1093/genetics/80.2.297.
The technique of countercurrent separation has been used to isolate 17 independent chemotaxis-defective mutants of the nematode Caenorhabditis elegans. The mutants, selected to be relatively insensitive to the normally attractive salt NaCl, show varying degrees of residual sensitivity; some are actually weakly repelled by NaCl. The mutants are due to single gene defects, are autosomal and recessive, and identify at least five complementation groups.
逆流分离技术已被用于分离线虫秀丽隐杆线虫的17个独立的趋化性缺陷突变体。这些突变体被选择为对通常具有吸引力的盐氯化钠相对不敏感，表现出不同程度的残余敏感性；有些实际上会被氯化钠微弱排斥。这些突变体是由单基因缺陷引起的，是常染色体隐性的，并确定了至少五个互补群。
